The hypoglycemic drug SGLT2 inhibitors also shows promising therapeutic effect on diabetes-induced renal tubular damage by restoring autophagy (156)
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Acylcarnitine is released from abnormal mitochondria in peripheral glial cells to affect surrounding axons, resulting in the destruction of axonal membrane properties and the induction of axonal degeneration, which has been shown to be neurotoxic [116]
Ferrari R, Merli E, Cicchitelli G, Mele D, Fucili A, Ceconi C: Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review
However, the accumulating data indicate that mitochondria are involved in the biogenesis of autophagosomes